FOXK1 (Forkhead Box K1) is a transcription factor that belongs to the forkhead box (FOX) family, distinguished by a unique DNA-binding domain known as the forkhead box. FOXK1 plays a vital role in regulating gene expression related to cell growth, proliferation, differentiation, and longevity. It is particularly significant in muscle development and regeneration, as well as in managing metabolic functions. Because of its involvement in these crucial processes, FOXK1 is also researched for its role in various diseases, including cancer.