AADAT (aminoadipate aminotransferase) is an enzyme that plays a vital role in the breakdown of lysine within the body. Primarily located in the mitochondria, it is involved in the alpha-aminoadipic semialdehyde (α-AASA) pathway, converting α-AASA to alpha-aminoadipate (AAA) — a crucial step in lysine degradation. This process helps regulate lysine levels and produces intermediates utilised in other metabolic pathways.