ADAMTS10 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs 10) is a gene that encodes a protein involved in the remodelling of the extracellular matrix, particularly in connective tissues. It plays a crucial role in tissue development and repair, especially in cartilage and bone. Variants in ADAMTS10 have been associated with connective tissue disorders and skeletal abnormalities.