ADGRL3 (Adhesion G Protein-Coupled Receptor L3) is a gene that encodes a protein in the adhesion G protein-coupled receptor family, which facilitates cell-to-cell communication and supports the development and function of the nervous system. It plays a key role in brain formation, neuronal signalling, and maintaining neural connectivity. Variations in ADGRL3 have been associated with neurological conditions, including attention deficit hyperactivity disorder (ADHD).