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ANGPTL4
ANGPTL4 (Angiopoietin-Like 4): ANGPTL4 is a multifunctional protein that plays key roles in regulating lipid metabolism, blood vessel formation (angiogenesis), and inflammation. It influences these processes by inhibiting lipoprotein lipase (LPL) activity, which increases plasma triglyceride levels, and by limiting endothelial cell migration and tube formation, affecting vascular growth and remodelling. Additionally, ANGPTL4 helps regulate inflammatory responses and tissue repair. Imbalances in ANGPTL4 function have been linked to metabolic conditions such as obesity, dyslipidaemia, and insulin resistance.
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