APBB1IP
APBB1IP (Amyloid Beta Precursor Protein-Binding Family B Member 1 Interacting Protein), also known as RIAM, is a protein that plays a crucial role in integrin activation, which is vital for cell adhesion and migration. By linking Rap1 GTPases to the actin cytoskeleton, APBB1IP facilitates cell attachment to the extracellular matrix, affecting immune cell function, wound healing, and tumour metastasis. Its role in these processes renders it significant for research into immune regulation and cancer.
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