ASB13

ASB13, also known as Ankyrin repeat and SOCS box protein 13, is a member of the ASB family of proteins, which are characterized by the presence of ankyrin repeat domains and a SOCS box domain. These proteins are involved in the regulation of protein degradation and signal transduction pathways within cells. One of the primary functions of ASB13 is its role as an E3 ubiquitin ligase, facilitating the ubiquitination and subsequent degradation of specific protein targets. The SOCS box domain of ASB13 interacts with components of the ubiquitin-proteasome system, including E2 ubiquitin-conjugating enzymes and Cullin-RING ligase (CRL) complexes, allowing ASB13 to...