CA8

CA8, also known as Carbonic Anhydrase VIII, is an enzyme belonging to the carbonic anhydrase family, which catalyzes the reversible hydration of carbon dioxide to bicarbonate ions and protons. Positioned predominantly within the cytoplasm and mitochondria of cells, CA8 plays a crucial role in maintaining pH homeostasis and regulating ion transport processes. One of the distinctive features of CA8 is its expression in various tissues, including the brain, kidneys, and reproductive organs, highlighting its diverse physiological roles beyond traditional carbonic anhydrase functions. Within the central nervous system, CA8 is particularly abundant in Purkinje cells of the cerebellum, where it is implicated...