CAVIN1 (Caveolae Associated Protein 1): CAVIN1 is a vital protein necessary for the formation and function of caveolae — small plasma membrane invaginations involved in processes such as endocytosis and signal transduction. It supports lipid metabolism, endothelial health, and cellular mechanoprotection. Mutations in CAVIN1 are linked to conditions like lipodystrophy and muscular dystrophies, emphasising its role in cell structure and metabolism.