COMT (Catechol-O-Methyltransferase): COMT is an enzyme that plays a crucial role in the metabolism of catecholamines, including dopamine, adrenaline, and noradrenaline. It is essential for regulating neurotransmitter levels in the brain and is associated with psychiatric disorders such as schizophrenia. COMT also contributes to the body's pain response and has been studied in connection with pain sensitivity and various mental health conditions.