Cortisol (total)

Cortisol is the primary glucocorticoid hormone produced by the adrenal glands and is commonly known as the “stress hormone.” It plays a vital role in regulating metabolism, immune response, blood pressure, and the body’s ability to respond to physical and emotional stress. Cortisol follows a daily rhythm, peaking in the early morning to support alertness and gradually decreasing throughout the day. Measuring total cortisol in blood reflects the combined levels of free and protein-bound cortisol, offering insight into adrenal function and overall hormone balance. Abnormal cortisol levels may be linked to conditions such as adrenal insufficiency, Cushing’s syndrome, chronic stress, or metabolic disorders.

Hormones