DHEA, produced by the adrenal glands, serves as a precursor to sex hormones. Its saliva measurement reflects active hormone levels, indicating the body's immediate DHEA production. This assessment helps in evaluating adrenal function, aging processes, and risk for chronic diseases....


Who would benefit from testing their DHEA levels?

Testing DHEA levels in saliva is beneficial for those experiencing symptoms of hormonal imbalances, such as fatigue, decreased libido, or mood swings. It’s also useful for individuals concerned about aging-related health issues or adrenal health.

What are symptoms of low or high DHEA levels?

High DHEA:

    • Oily skin and acne
    • Hair loss
    • Increased aggression or irritability
    • Menstrual irregularities in women


    • Decreased muscle mass and strength
    • Aging skin
    • Reduced sex drive
    • Lower immunity

What is the difference between DHEA and DHEA-S?

DHEA (Dehydroepiandrosterone) and DHEA-S (Dehydroepiandrosterone Sulfate) are both hormones produced by the adrenal glands, but they differ in their biological roles and stability. DHEA acts as a precursor to sex hormones like estrogen and testosterone. It is rapidly fluctuating and sensitive to the body’s immediate needs. In contrast, DHEA-S is a sulfate ester form of DHEA. It is more abundant and stable in the bloodstream, providing a longer-term indicator of adrenal function and overall health. DHEA-S is not directly involved in producing sex hormones but reflects the body’s DHEA reserve.

What is the difference between testsing DHEA in saliva and DHEA-S in blood?

Testing DHEA in saliva and DHEA-S in blood provides different insights due to the nature of these compounds and the mediums in which they are measured.

  • DHEA in Saliva: This test measures the free, bioavailable form of DHEA, reflecting the body’s immediate response to adrenal gland activity. It is more indicative of the current, active level of DHEA in the body, which can fluctuate significantly throughout the day or in response to stress.
  • DHEA-S in Blood: The blood test measures the level of DHEA-S, which is more stable and provides an overview of the long-term adrenal function. It’s a better indicator of the body’s overall reserve and capacity to produce DHEA over time rather than the immediate levels.

Test(s) that measure/test for DHEA

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