Dihomo-gamma-linolenic acid (DGLA)

Dihomo-gamma-linolenic acid (DGLA) is an Omega-6 fatty acid, a derivative of gamma-linolenic acid (GLA), and a precursor to important eicosanoids. DGLA plays a unique role in the body's inflammatory processes, often acting to suppress inflammation and support cardiovascular health....

Dihomo-gamma-linolenic acid (DGLA)

What is dihomo-gamma-linolenic acid (DGLA)?

Dihomo-gamma-linolenic acid (DGLA) is a long-chain polyunsaturated fatty acid in the omega-6 family. It’s formed in the body from gamma-linolenic acid (GLA) and can be further converted to arachidonic acid (AA). DGLA is a precursor to a series of prostaglandins that are anti-inflammatory, which is notable given that many other omega-6 fatty acids are associated with pro-inflammatory pathways.

Who would benefit from testing DGLA levels?

  • Individuals with chronic inflammatory conditions, as DGLA can influence inflammation.
  • People suffering from skin disorders like eczema or psoriasis.
  • Individuals at risk of cardiovascular diseases, as DGLA may have beneficial effects.
  • Those interested in optimizing their fatty acid profile for general health.

What is the role of DGLA in the body?

DGLA is an important intermediary in the metabolism of Omega-6 fatty acids. It’s involved in the production of anti-inflammatory prostaglandins, which help regulate the inflammatory response in the body. DGLA also contributes to the maintenance of healthy cell membranes and can modulate immune function. Its role in the production of eicosanoids means it’s involved in a wide range of physiological processes, including those affecting the cardiovascular system and skin health.

What are the symptoms of DGLA deficiency?

  • Increased inflammatory responses.
  • Worsening of inflammatory skin conditions.
  • Potential increase in the risk of developing cardiovascular diseases.
  • Possible impact on immune system functioning.
  • Disruptions in normal hormonal balance and related issues.

Test(s) that measure/test for Dihomo-gamma-linolenic acid (DGLA)

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