EPHB2 (Ephrin Type-B Receptor 2): EPHB2 is a receptor tyrosine kinase that plays a key role in cell-to-cell communication and tissue organisation. By interacting with ephrin ligands, EPHB2 regulates important processes such as cell migration, adhesion, and axon guidance during development and throughout life. It is essential for maintaining the structure and function of tissues, especially in the nervous system and epithelial layers. Dysregulation of EPHB2 signalling has been linked to conditions like cancer progression, neurodevelopmental disorders, and tissue malformations.