FHOD3 (Formin Homology 2 Domain Containing 3): FHOD3 is a member of the formin family of proteins, which play a crucial role in the organization and regulation of the actin cytoskeleton. This protein is particularly significant in cardiac muscle and other tissues, where it facilitates the assembly of actin filaments, thereby influencing cell shape, adhesion, and motility. FHOD3's activity is pivotal during cell division, migration, and muscle contraction, contributing to the proper functioning of cardiovascular and skeletal systems. Its regulatory mechanisms involve the dynamic remodeling of the actin cytoskeleton, essential for heart development and function. Dysregulation of FHOD3 has been implicated in cardiovascular diseases, including hypertrophic cardiomyopathy and heart failure, underscoring its potential as a therapeutic target. The precise modulation of FHOD3 activity is vital for maintaining cellular and tissue architecture, mirroring its broader significance in health and disease.


Test(s) that measure/test for FHOD3

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