FLT3 (Fms-Like Tyrosine Kinase 3): FLT3 is a receptor tyrosine kinase involved in the proliferation and differentiation of haematopoietic stem cells into mature blood cells. Mutations in FLT3, especially activating mutations, are commonly seen in acute myeloid leukaemia (AML) and are linked to poor prognosis. Targeting FLT3 with inhibitors is a therapeutic approach used to treat AML and other blood cancers with FLT3 mutations.