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GGT
Gamma-glutamyl transferase (GGT) is an enzyme present throughout the body, with the highest concentrations in the liver. GGT plays a crucial role in glutathione metabolism, which is essential for antioxidant defence. It facilitates the transfer of amino acids and peptides across cell membranes. Raised GGT levels are commonly used as a marker to detect liver damage, particularly bile duct obstruction and liver conditions associated with alcohol consumption.
Description
- Individuals exhibiting signs of liver disease or damage, such as jaundice or abdominal pain.
- Patients with a history of alcohol abuse, as GGT can be an indicator of alcohol-induced liver damage.
- Those with known or suspected bile duct obstructions.
- People with conditions that might impact the liver, such as hepatitis or fatty liver disease.
- Individuals on medications known to affect the liver.
- Jaundice (yellowing of skin and eyes)
- Abdominal pain or discomfort
- Nausea and vomiting
- Fatigue
- Dark urine
- Itchy skin
High GGT levels can be caused by:
- Liver diseases such as hepatitis, cirrhosis, or liver cancer.
- Bile duct obstructions.
- Alcohol abuse leading to liver damage.
- Use of certain medications or drugs toxic to the liver.
- Pancreatic diseases.
- Heart failure.
- Limit alcohol intake or abstain entirely, especially if alcohol use is the underlying cause.
- Follow a balanced diet and maintain a healthy weight to reduce the risk of fatty liver disease.
- Exercise regularly to improve overall liver health and function.
- Avoid unnecessary medications or substances that could harm the liver.
- Regularly monitor and manage any underlying health conditions, especially those related to liver or heart health.
- Consult with healthcare providers for specific treatments and lifestyle recommendations based on the underlying cause of elevated GGT.
Tests containing this item
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