HERC2

HERC2 (HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2): HERC2 is an E3 ubiquitin-protein ligase, playing a key role in the ubiquitin-proteasome system, which regulates protein degradation. HERC2 is involved in various cellular processes, including DNA repair and the regulation of pigment production, particularly in eye color determination. Mutations or alterations in HERC2 are associated with neurodevelopmental disorders and pigmentary anomalies.

HERC2

Test(s) that measure/test for HERC2

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