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Herpes Simplex Virus (HSV) IgM antibodies are immune proteins that may develop as part of the body’s immune response to herpes simplex virus, including HSV-1 and/or HSV-2. IgM antibodies are sometimes associated with a recent immune response, but they can be difficult to interpret and may also appear during recurrent infections. A positive result does not confirm an active infection and does not distinguish between HSV-1 and HSV-2.

