IKBIP

IKBIP (Inhibitor of Kappa Light Polypeptide Gene Enhancer in B-Cells, Inhibitor Protein): IKBIP is involved in the negative regulation of NF-κB signaling, a pathway critical for immune response, inflammation, and cell survival. It acts by inhibiting the activity of NF-κB in the cytoplasm, preventing its translocation to the nucleus and activation of target genes. Dysregulation of NF-κB signaling through IKBIP has implications in autoimmune diseases, chronic inflammation, and cancer, emphasizing its role in controlling immune and inflammatory responses....