IKZF2 (IKAROS Family Zinc Finger 2): IKZF2, also known as Helios, is a transcription factor important in the development and function of the immune system, particularly in T-cell differentiation and regulation. Mutations or dysregulation in IKZF2 can have significant implications in autoimmune diseases and in certain leukemias, making it a crucial gene in immunology and hematologic malignancies.


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