INSR

INSR, or Insulin Receptor, is a transmembrane receptor protein that plays a crucial role in mediating the biological effects of insulin, a hormone involved in the regulation of glucose metabolism, lipid metabolism, and cellular growth. INSR is primarily found on the surface of target cells, such as adipocytes, hepatocytes, and skeletal muscle cells. One of the primary functions of INSR is its involvement in insulin signaling pathways. Upon binding of insulin to the extracellular domain of INSR, the receptor undergoes conformational changes, leading to autophosphorylation of tyrosine residues in its intracellular domain. This phosphorylation event activates the receptor's tyrosine kinase activity,...