IREB2

IREB2 (Iron Responsive Element Binding Protein 2): IREB2 plays a key role in iron metabolism by regulating the expression of genes involved in iron storage and transport. It is crucial in maintaining iron homeostasis in the body, binding to iron-responsive elements (IREs) in the mRNA of these genes to modulate their stability and translation. Imbalances in iron levels, whether due to deficiency or overload, can lead to various health issues, including anemia or iron overload disorders like hemochromatosis. The study of IREB2 is particularly significant in understanding iron-related metabolic pathways and their implications in conditions such as neurodegenerative diseases, where...