ITIH3 (Inter-Alpha-Trypsin Inhibitor Heavy Chain 3): ITIH3 is a protein belonging to the inter-alpha-trypsin inhibitor family, involved in stabilising the extracellular matrix and modulating inflammation. It plays a role in tissue repair and protecting against protease-related tissue damage. Dysregulation of ITIH3 has been linked to cancer progression and inflammatory diseases, emphasising its role in tissue homeostasis and the immune response.