MAT1A (Methionine Adenosyltransferase I, Alpha) is essential for the synthesis of S-adenosylmethionine (SAMe), a major methyl donor involved in numerous metabolic processes. This enzyme's activity is critical for methionine metabolism and regulates gene expression, cell proliferation, and the detoxification process. MAT1A dysfunction can lead to liver diseases such as cirrhosis and hepatocellular carcinoma. Understanding MAT1A's role highlights its importance in liver health, potential diagnostic markers, and therapeutic targets for liver disorders....