MICAL2
MICAL2 (Molecule Interacting with CasL 2): MICAL2 is an enzyme belonging to the MICAL family, recognised for regulating cytoskeletal dynamics through the oxidation of actin. MICAL2 plays a key role in controlling the disassembly of actin filaments, which influences cell shape, migration, and intracellular transport. Its activity is essential for processes such as neurite outgrowth, axon guidance, and the maintenance of synaptic and vascular structures. By modulating the cytoskeleton, MICAL2 supports cell communication, differentiation, and movement. Dysregulation of MICAL2 has been linked to cancer progression, neurological disorders, and vascular diseases.
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