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MTHFD1 Gene | Role in Folate Metabolism & Health Risks

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Discover the MTHFD1 gene's role in folate metabolism and how its mutations can lead to health issues like neural tube defects and cardiovascular disease.

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MTHFD1 (Methylenetetrahydrofolate Dehydrogenase 1): MTHFD1 is a crucial enzyme in the folate metabolism pathway, catalysing the conversion of tetrahydrofolate (THF) derivatives into forms used for the synthesis of DNA, RNA, and amino acids. It plays a vital role in one-carbon metabolism, influencing cellular methylation reactions and nucleotide production. Mutations or dysregulation of MTHFD1 can disrupt folate metabolism and are associated with an increased risk of congenital defects, cardiovascular diseases, and cancer.

MTHFD1

Saliva Tests

The DNA genetic Methylation Test from GetTested provides a comprehensive analysis of your body's methylation capabilities by exploring key genes such as MTHFR, COMT, BHMT, and several others. We also offer a <a href="/product/dna-methylation-plus-test">DNA Methylation Plus Test</a> that, in addition to this test, also analyzes AHCY and more.
By analyzing these genes, the test offers insights into how your body manages crucial biological processes like gene expression, DNA repair, and detoxification. Methylation plays a vital role in many of the body's functions and can influence everything from energy production to mental well-being.
This test is ideal for those seeking a deeper understanding of their health at a molecular level and wishing to tailor their diet, lifestyle, and potential supplements based on personal genetic predispositions.
You can easily collect your saliva sample with the included test kit and send it to our lab. The price covers the return shipping. You'll receive your detailed results digitally within 6-8 weeks.
Save more by bundling DNA tests. Order <a href="/product/dna-combo-3-order-any-3-tests">multiple tests</a> together for better value from our wide range.

MTHFD1

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