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MTHFR
MTHFR (Methylenetetrahydrofolate Reductase): MTHFR is an enzyme that plays a central role in folate metabolism and the regulation of homocysteine levels. It converts 5,10-methylenetetrahydrofolate into 5-methyltetrahydrofolate, allowing the remethylation of homocysteine to methionine — a precursor to S-adenosylmethionine (SAM), the body’s primary methyl donor. Variants in the MTHFR gene, such as C677T and A1298C, can affect enzyme activity, potentially altering folate metabolism, raising homocysteine levels, and impacting methylation-dependent processes like DNA methylation and neurotransmitter synthesis.
Description
Tests containing this item
16 genes
Lab TestThe DNA genetic Methylation Test from GetTested provides a comprehensive analysis of your body's methylation capabilities by exploring key genes such as MTHFR, COMT, BHMT, and several others. We also offer a DNA Methylation Plus Test that, in addition to this test, also analyzes AHCY and more.
199.00 GBP
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