MTHFR (Methylenetetrahydrofolate Reductase): MTHFR is an enzyme crucial for folate metabolism, converting 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, essential for converting homocysteine to methionine. Methionine is vital for creating SAM, a methyl donor involved in DNA methylation and neurotransmitter synthesis. Variants like C677T and A1298C in the MTHFR gene can lead to high homocysteine levels and impact methylation, affecting cardiovascular health, neural tube defects, and pregnancy outcomes. Genetic testing for these polymorphisms helps guide personalized treatments, including folate supplementation....


Test(s) that measure/test for MTHFR

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