NBR1 (Neighbour Of BRCA1 Gene 1): NBR1 is a multifunctional autophagy receptor that regulates selective autophagy — the targeted degradation and recycling of cellular components. It helps remove ubiquitinated protein aggregates and damaged organelles, supporting cellular homeostasis and protection against stress. Its role in autophagy is closely linked to disease prevention, including neurodegenerative disorders, cancer, and age-related conditions, emphasising its importance in cellular health and longevity.