NCF4

NCF4 (Neutrophil Cytosolic Factor 4): NCF4 is a component of the NADPH oxidase complex, playing an essential role in the immune defense against pathogens. It participates in the generation of reactive oxygen species in phagocytes, which is crucial for the microbial killing. Mutations in NCF4 have been associated with chronic granulomatous disease, characterized by recurrent bacterial and fungal infections.

NCF4

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