NDUFA11
NDUFA11 (NADH:Ubiquinone Oxidoreductase Subunit A11): NDUFA11 is a gene that encodes a protein subunit of mitochondrial complex I, the first and largest enzyme complex in the electron transport chain. It supports the assembly, stability and electron transfer of complex I from NADH to ubiquinone, aiding in the generation of the proton gradient necessary for ATP production via oxidative phosphorylation. Mutations in NDUFA11 can impair energy metabolism and contribute to mitochondrial diseases and related disorders.
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