P2RY1
P2RY1 (Purinergic Receptor P2Y1): P2RY1 is a G-protein coupled receptor that responds to extracellular nucleotides such as ATP and ADP. It plays a crucial role in intracellular signalling pathways involved in platelet aggregation, regulation of vascular tone, and neurotransmission. Activation of P2RY1 is essential for triggering platelet aggregation following vessel injury, emphasising its importance in thrombosis and haemostasis. Dysregulation of P2RY1 signalling is associated with an increased risk of cardiovascular diseases, highlighting its significance in vascular health.
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