PLCG2 (Phospholipase C Gamma 2): PLCG2 is a gene that plays a crucial role in intracellular signalling pathways, particularly in immune cells. It is involved in the hydrolysis of phosphatidylinositol 4,5-bisphosphate, a key step in activating the protein kinase C pathway. Mutations in PLCG2 have been associated with immune-related disorders and are researched in connection with autoinflammatory diseases.