RAPGEF6 (Rap Guanine Nucleotide Exchange Factor 6): RAPGEF6 is a protein that plays a crucial role in signal transduction pathways, regulating cell adhesion, migration, and growth. It acts as a guanine nucleotide exchange factor for Rap proteins, controlling their activity in response to extracellular signals. Dysregulation of RAPGEF6 has been associated with cancer progression and metastasis, highlighting its significance in cellular signalling and the regulation of cell dynamics.