RGS6 (Regulator of G Protein Signalling 6): RGS6 is a member of the RGS family that plays a crucial role in regulating G protein-coupled receptor (GPCR) signalling pathways. It accelerates the GTPase activity of G protein α subunits, effectively switching off GPCR signalling and acting as a key modulator of signal transduction. This regulation is essential for various physiological processes, including sensory perception, cardiovascular control, and central nervous system function. By fine-tuning GPCR signalling, RGS6 helps control cellular responses to external stimuli.