RNF144B

RNF144B, also known as Ring Finger Protein 144B, is a member of the RING finger protein family, characterized by the presence of a RING (Really Interesting New Gene) domain, which confers E3 ubiquitin ligase activity. Positioned predominantly within the cytoplasm or nucleus of cells, RNF144B plays a crucial role in the regulation of protein degradation and cellular signaling pathways. One of the primary functions of RNF144B is its involvement in the ubiquitin-proteasome system, a major pathway for protein degradation in eukaryotic cells. As an E3 ubiquitin ligase, RNF144B catalyzes the transfer of ubiquitin molecules onto substrate proteins, targeting them for degradation...