SDHAF3 (Succinate Dehydrogenase Complex Assembly Factor 3): SDHAF3 is a gene involved in the assembly of the succinate dehydrogenase complex, a crucial part of the mitochondrial electron transport chain. This protein helps to maintain the proper functioning of the complex, supporting efficient energy production. Mutations in SDHAF3 can disrupt mitochondrial activity and contribute to mitochondrial disorders, emphasising its significance in cellular health.