SGK1 (Serum/Glucocorticoid Regulated Kinase 1): SGK1 is a serine/threonine kinase regulated by glucocorticoids, involved in cell survival, ion transport, and metabolic regulation. It aids the body’s response to stress and regulates ion channel activity, especially in the kidneys, affecting sodium and water balance. Dysregulation of SGK1 has been associated with hypertension, diabetic nephropathy, and certain cancers.