SPG7

SPG7 (Spastic Paraplegia 7, Paraplegin): SPG7 is a mitochondrial protein that plays a role in the maintenance and function of mitochondria, particularly in the ATPase assembly. Mutations in SPG7 are a common cause of hereditary spastic paraplegia, a neurodegenerative disorder characterized by progressive stiffness and weakness of the lower limbs, reflecting its importance in neural and mitochondrial function....

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