STAT6 (Signal Transducer And Activator Of Transcription 6) is a protein that plays a central role in immune signalling pathways, particularly those activated by cytokines such as IL-4 and IL-13. It regulates allergic inflammation by promoting the development of Th2 cells, the production of IgE antibodies, and the proliferation of mast cells. Due to its involvement in allergic reactions and asthma, STAT6 is a significant target for therapies designed to control immune responses in allergic conditions.