TBX3 (T-Box Transcription Factor 3): TBX3 is a transcription factor that plays a crucial role in embryonic development, regulating organogenesis including the formation of limbs, heart, and mammary glands. Mutations or dysregulation of TBX3 can result in developmental disorders such as ulnar-mammary syndrome. It is also involved in cancer, where it may function as a transcriptional repressor to inhibit cellular senescence and promote cell proliferation.