TET2 (Tet Methylcytosine Dioxygenase 2): TET2 is an enzyme that catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine in DNA, playing a key role in active DNA demethylation. This process is crucial for the regulation of gene expression, cellular differentiation, and the maintenance of genomic stability. Mutations in TET2 are commonly found in various hematological malignancies, such as myelodysplastic syndromes and acute myeloid leukemia, implicating TET2 in epigenetic regulation and the pathogenesis of cancer.


Test(s) that measure/test for TET2

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