TGFBR2 (Transforming Growth Factor Beta Receptor 2): TGFBR2 is a gene that encodes a key component of the TGF-beta signalling pathway, which regulates cell growth, differentiation, and immune responses. Mutations in TGFBR2 are linked to hereditary conditions such as hereditary haemorrhagic telangiectasia (HHT) and may contribute to the development of certain cancers.