TMPRSS4 (Transmembrane Protease, Serine 4): TMPRSS4 is a member of the transmembrane serine protease family, known for its role in processing various proteins involved in physiological and pathological processes. This enzyme is localized on the cell surface, where it participates in the activation of proteins by cleaving peptide bonds. TMPRSS4 has been implicated in several critical biological pathways, including cell migration, invasion, and the regulation of epithelial-mesenchymal transition (EMT), which is pivotal in development, wound healing, and cancer metastasis. Its overexpression is associated with the progression of various cancers, making TMPRSS4 a potential biomarker for cancer diagnosis and prognosis, as well as a promising target for therapeutic intervention. By modulating cellular processes such as adhesion, invasion, and proliferation, TMPRSS4 plays a significant role in tumor biology and represents a link between proteolytic activity and cancer pathogenesis.


Test(s) that measure/test for TMPRSS4

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