TNXB

TNXB (Tenascin-XB): TNXB, a member of the tenascin family of extracellular matrix proteins, plays a pivotal role in tissue development, organization, and homeostasis. It is primarily expressed in connective tissues, where it contributes to the structural integrity and elasticity of the extracellular matrix (ECM). TNXB is involved in cell adhesion, migration, and proliferation, influencing processes such as wound healing, tissue remodeling, and organogenesis. Its expression is particularly prominent in skin, tendons, and blood vessels, where it modulates the mechanical properties and resilience of these tissues. Mutations or deficiencies in TNXB have been associated with Ehlers-Danlos syndrome (EDS), a group of...