TOMM40 (Translocase of Outer Mitochondrial Membrane 40): TOMM40 is a key protein involved in mitochondrial function, specifically in importing proteins into the mitochondria. As part of the TOM complex, TOMM40 assists in transporting nuclear-encoded proteins across the outer mitochondrial membrane so they can perform essential roles within the mitochondria. Variants of TOMM40 are notably linked to Alzheimer's disease, affecting the risk and age of onset. It has also been associated with other neurodegenerative disorders and age-related cognitive decline.