Putrescine is a biogenic amine produced through the bacterial and cellular breakdown of the amino acid ornithine. It is involved in cell growth, tissue regeneration, and the regulation of intestinal function. Elevated putrescine levels can occur due to increased microbial fermentation, protein degradation, or intestinal dysbiosis. Balanced levels reflect normal gut metabolic activity and effective detoxification processes.
High putrescine levels are often associated with increased intestinal microbial activity or dysbiosis. Individuals may experience bloating, flatulence, abdominal discomfort, or irregular bowel movements. In some cases, elevated levels may also indicate impaired detoxification or protein metabolism.
Testing putrescine can be beneficial for those experiencing chronic digestive symptoms, suspected gut dysbiosis, or unexplained fatigue. It can also offer valuable insights for individuals with protein metabolism problems, liver strain, or microbial overgrowth such as SIBO.
Putrescine is produced during the bacterial and cellular breakdown of amino acids, particularly ornithine. Diet, microbial balance, protein intake, and detoxification capacity all affect its levels. Poor gut health or an imbalanced microbiota can lead to accumulation.
Yes. Supporting gut microbial balance, ensuring efficient digestion, and promoting detoxification pathways can help reduce elevated putrescine. A balanced diet rich in fibre, antioxidants, and adequate hydration supports healthy intestinal and metabolic function.