PDXK
The PDXK gene encodes the enzyme pyridoxal kinase, which is crucial for converting vitamin B6 into its active form, pyridoxal-5′-phosphate (PLP). PLP acts as a coenzyme in over 100 enzymatic reactions, many of which are involved in amino acid metabolism, neurotransmitter synthesis, and energy production. Variants in the PDXK gene may impair this conversion, potentially leading to a functional vitamin B6 deficiency even if B6 intake is adequate. Disruption in PLP levels has been associated with neurological symptoms, fatigue, and mood disturbances.
Description
It produces pyridoxal kinase, an enzyme responsible for converting vitamin B6 into its active form, PLP.
PLP functions as a coenzyme in numerous vital processes, including neurotransmitter synthesis, amino acid metabolism, and energy pathways.
Impaired conversion of B6 to PLP may lead to symptoms of B6 deficiency, such as low mood, fatigue, or neurological problems.
Yes, if PDXK function is impaired due to genetic variants, B6 may not be efficiently converted into PLP despite sufficient dietary intake.
Trusted by over 100.000+ customers
The home test was straightforward with easy to follow instructions. The test result was detailed and clear in its presentation. Also had the opportunity to ask questions about the test result.
Richard
We looked at a lot of companies offering the same services but made the decision to go forward with get tested because the labs are based here in the UK. The process has been very straight forward.
Natasha
There are other providers out there, I have tried 3. Gettested was the fastest and the customer service was the best. I even received my test on the day of purchase delivered by a motorbike courier.
Alan
Absolutely perfect, results came after few days and finally after a lots of times visited GP, we finally know why my son has eczema - he is allergy to carrot. Thanks a lot.
E
I found them to be professional and not too long a wait for results. Helpful with any after questions. Will be using them again if need be. I highly recommend them.
Eileen