Histamine Intolerance Test

Test type
Lab Test

We offer two types of tests; Lab Tests and Rapid Tests. This product is under the category Lab Tests. See all our Lab Tests by following the link.

See all
Collection method

We offer several different options of testing methods. This test is done with Blood. See all tests done with Blood by following the link.

See all

Original price was: £ 69,00.Current price is: £ 49,00.

Determine the cause behind symptoms such as headaches, stomach discomfort, and itching with GetTested’s Histamine Intolerance Test. This home-based blood test measures DAO enzyme levels to assess if histamine intolerance is the underlying issue, providing a clear path to managing your symptoms effectively.

Since histamine intolerance and allergies can present with similar symptoms, we also offer an Allergy Test for those looking to explore potential allergic reactions further.

  • In stock

  • At-home tests
  • Fast delivery

37 in stock

Extra services for your order?
People buying this test also typically buy
brand cards

Get 5% off on 2 Lab tests, and 10% off on 3 Lab tests or more.

EAN: 0616612786951 SKU: 3DA/061 Category: Tag:

About Our Histamine Intolerance Test

Histamine intolerance can be elusive and difficult to pin down. Common symptoms such as headaches, stomach problems, and itching often resemble an allergic reaction, making it challenging to discern without specific testing. Our Histamine Intolerance Test, carried out in a UK-based ISO 13485 certified lab, provides answers by analysing your blood for DAO enzyme concentration. DAO, or Diamine oxidase, is vital for breaking down histamine in the body.

DAO and Histamine

Diamine oxidase (DAO) is a digestive enzyme responsible for breaking down excess histamine in the body. DAO deficiency, which can present when DAO enzyme activity is low, leads to alterations in histamine metabolism. [source] When you don’t have enough DAO enzyme, you can get histamine intolerance. 

The role of histamine in the body is to regulate your sleep-wake cycle and cognitive function, but it is most known for the fact that it causes allergy symptoms. When your body receives an allergy trigger, it will respond by getting rid of it. When the histamines start the process of removing the unwanted trigger out of your body or skin, this can cause allergic symptoms such as sneezing or itching. The body works hard by sending loads of histamines to keep you safe, but its overreaction causes the unpleasant allergy symptoms.

The type of effect histamine has on your body is dependent on which histamine receptors it binds to. There exist four types of histamine receptors:

  • H1 receptors are present throughout the body. They cause the most well-known allergy symptoms such as: itchy skin, nasal congestion, runny nose and sneezing. 
  • H2 receptors reside mostly in the stomach and cause allergy symptoms such as: Stomach acid secretion, headache. The excess stomach acid is created to battle the trigger that has invaded the body. 
  • H3 receptors are found in the central nervous system, where they help regulate the release of histamine and neurotransmitters.
  • H4 receptors play a role in blood-cell formations and are present in the bone marrow and immature cells (hematopoietic cells). 

Understanding the Symptoms

Common symptoms include headache, migraine, dizziness, redness, itching, swelling, stomach and intestinal issues, cough, asthma, runny nose, difficulty swallowing, changes in blood pressure and palpitations. Symptoms can vary from mild, like a recurring headache, to more severe reactions.

The symptoms are heavily dependent on the histamine receptors, as previously mentioned. H1 receptors are linked to symptoms associated with having a cold, such as runny nose and coughing, but also itchiness. On the other hand, H2 receptors are the ones causing stomach and intestinal issues, as well as headaches. 

Histamine Intolerance Treatment

To get rid of the symptoms, you must clear histamine from your body. There are several ways you can treat the symptoms:

H1 Antihistamines: These antihistamines will block the H1 receptors responsible for allergic symptoms caused by a pollen allergy or pet allergy. This will reduce symptoms. You can purchase H1 antihistamines as tablets, liquids, creams, and eye drops.

H2 Antihistamines: These antihistamines block the H2 receptors and by doing so help treat several digestive issues. 

Low histamine diet: Avoiding histamine-rich foods and drinks can help reduce symptoms. High histamine foods are foods that are aged. Alcohol as well is particularly high in histamine. In the list of low histamine foods, you can find many fruits such as apples, mangos, peaches and blueberries, and vegetables such as onions, broccoli, cucumbers, asparagus and sweet potatoes. Fresh meat and fish are also recommended, but note that spoiled fish can build up high levels of histamine as well, so make sure to eat fish that has been kept at safe temperatures.

Supplements: DAO supplements can also be beneficial. Studies have shown, Vitamin C and Vitamin B6 may also be beneficial in lowering histamine levels. Consult with a dietist/practitioner, before taking any supplements. 

 Other Tests That May Be of Interest

  • Allergy Test: Measures both foods, pollen and pet dander. Can give similar reaction as histamine intolerance.
  • Food Intolerance Test: Understand your body’s reaction to more than 240 different foods.
  • Stress Hormone Test: Measure your body’s response to stress.
  • Nutrient Test: Find out if you’re getting the vitamins and minerals your body needs.

Not Sure This Test is for You?

If you’re still uncertain whether this test is right for you, don’t hesitate to reach out to our friendly and knowledgeable customer support team. We’re here to guide you towards the tests that best match your health concerns and objectives. You can contact us through our contact page or use our live chat for immediate assistance.


How is the Histamine intolerance test carried out?

Our Histamine intolerance test is a home test kit. After ordering, we will send you a kit with everything you need to collect a small blood sample. Then, simply return your sample to us in the pre-paid envelope.

Who Can Benefit from the Histamine Intolerance Test?

Testing DAO levels is beneficial for individuals experiencing symptoms of histamine intolerance, such as headaches, skin irritation, or digestive issues. It’s also useful for those with allergies, gastrointestinal disorders, or those seeking to understand unexplained symptoms related to histamine activity.

What happens if I fail to take the sample?

If you read the instructions carefully before you take the test and it should go well. Should something go wrong, you are welcome to contact us and we will help you.

How quickly will I receive my results?

Once we receive your sample, the average response time is 10-15 business days to receive the results.

When should I take the test?

It is recommended to take the test on an empty stomach in the morning.

What is the difference between histamine intolerance and allergy?

Histamine intolerance and allergies can produce similar symptoms, but their causes differ. Histamine intolerance is due to the body's inability to efficiently break down histamine, leading to accumulation. Allergies, on the other hand, are immune responses to specific allergens.

How do you carry out the Histamine Intolerance Test?

Our Histamine Intolerance Test is a home test kit. After ordering, we will send you a kit with everything you need to collect a small blood sample. Then, simply return your sample to us in the pre-paid envelope.

Who should get a Histamine intolerance test?

The test is suitable to anyone suffering from the allergy symptoms caused by histamine. 

Is histamine intolerance treatable?

Yes, histamine intolerance can often be managed by taking DAO supplements and by avoiding foods rich in histamines, as well by taking antihistamines. 

What is DAO?

DAO, or Diamine oxidase, is an enzyme that breaks down histamine in the body.

Can children take the Histamine Intolerance Test?

Our test is suitable for individuals of all ages, but children under 18 require parental consent.

Example Report

pdf icon

Example of Histamine Intolerance Test


10 reviews
5 stars
4 stars
3 stars
2 stars
1 stars
  • Drew
    nice! :)
  • Rajiv
    Being an avid fan of wine and aged cheeses, I was taken aback when I started experiencing migraines and digestive discomfort. A friend mentioned histamine intolerance, so I sought out the Histamine Intolerance Test. The kit was straightforward and user-friendly, and I appreciated the hassle-free process. The comprehensive results provided clarity I desperately needed. Realizing that some of my favourite foods were contributing to my ailments was a tough pill to swallow. Armed with this information, however, I revamped my diet. The improvement was swift and significant. I am now more mindful of my choices and enjoy a symptom-free life, all thanks to this test.

Related Products

You may also like…

  • food intolerance 40 items test
    40 items

    Food Intolerance 40 items

    Sale! Original price was: £ 79,00.Current price is: £ 69,00. Add to basket
  • Gut Microbiome test SMALL UK
    18 items

    Gut Microbiome Test Small

    £ 99,00 Add to basket
  • Allergy Test Small
    38 items

    Allergy Test Small

    Sale! Original price was: £ 79,00.Current price is: £ 49,00. Add to basket
    1 item

    Celiac/Gluten Intolerance Test

    £ 19,00 Add to basket

Trusted by over 10.000+ customers

gettested trust pilot